Table 2 Summary table ranking the different EV separation methods based on the different characteristics assessed in this study and providing an overall rank for suitability of use for clinically relevant plasma EV biomarker investigation. Scored from 1 (highest) to 5 (lowest), = equivalent rank
|  | dUC | dUC + f | TEIR | SEC | Mag |
|---|---|---|---|---|---|
Yield | 3 | 4 | 1 =  | 1 =  | 5 |
Enrichment | 1 | 2 | 5 | 3 | 4 |
Size | 1 =  | 1 =  | 1 =  | 1 =  | 1 =  |
Representability of Tetraspanin distribution | 2 | 3 | 4 | 1 | 5 |
Proteomics | 1 | 3 =  | 5 | 2 | 3 =  |
Ease of use | 4 =  | 4 =  | 1 =  | 1 =  | 3 |
Overall rank | 2 | 3 =  | 3 =  | 1 | 5 |