Table 2 Efficiency of CRISPR-Cas9 mediated genomic editing by cytoplasm microinjection
From: CRISPR-mediated generation and comprehensive phenotyping of Duchenne Muscular Dystrophy mouse models
Strain | No. of injected zygotes | No. of surviving zygotes | No. of Transferred Zygotes | No of Pups/Zygotes (%) | No of Mutant Founders/Pups (%) |
|---|---|---|---|---|---|
mDMD Exon 51 KO (ΔEx51) | 136 | 126 (92%) | 120 | 15 (13%) | 9 (60%) |
mDMD Exon 52 KO (ΔEx52) | 103 | 92 (89%) | 69 | 26 (38%) | 19 (73%) |