Fig. 3

Validation of scAI-SNP for ancestry inference. a Inferred ancestry from single-cell RNAseq data of bone marrow mononuclear cells from 5 donors with known self-reported race. The vertical bar plots depict the predicted contribution of each of the 26 population groups to each donor. These probabilities are plotted again in horizontally stacked bar plots on the right in a more succinct form. The percentages on the right side are the fraction of the 4.5 million ancestry-informative SNP sites detected in each sample. b Same plots as in (a) for 2 samples from donors who self-reported as White. Ancestry inferred from whole genome sequencing of DNA extracted from the peripheral blood of these donors yielded results consistent with those from scRNA-seq samples