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Fig. 5 | BMC Methods

Fig. 5

From: scAI-SNP: a method for inferring ancestry from single-cell data

Fig. 5

scAI-SNP results from scRNA-seq and WGS of cancer cells. Pie charts show the inferred ancestry (ancestry group with the largest predicted probability) across all the scRNA-seq tumor samples for a given individual across 41 individuals in the MSK SPECTRUM Ovarian Cancer dataset. The number of samples for each individual is shown in the center of the pie chart. The schematic shows approximately the different regions from which the samples were obtained. For individuals O_ID01, O_ID07, O_ID36, and O_ID41, the stacked predicted probabilities are shown along with the labels on the left that indicate which tissue was used and on the right that show the fraction of the 4.5 million ancestry-informative SNP sites detected in each sample. Note that multiple scRNA-seq samples may originate from the same site. For those 4 individuals, we also show the inferred ancestry using their respective WGS of normal and tumor tissues

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